Detalhe da pesquisa
1.
Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages.
Cell
; 184(11): 2988-3005.e16, 2021 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019793
2.
Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy.
Bioorg Med Chem Lett
; 29(20): 126640, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31500996
3.
Hypoxia-activated prodrug and antiangiogenic therapies cooperatively treat pancreatic cancer but elicit immunosuppressive G-MDSC infiltration.
JCI Insight
; 9(1)2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37988164
4.
Identification of Nonfunctional Alternatively Spliced Isoforms of STING in Human Acute Myeloid Leukemia.
Cancer Res Commun
; 4(3): 911-918, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38477596
5.
KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response.
bioRxiv
; 2023 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711647
6.
KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response.
J Immunother Cancer
; 11(9)2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657842
7.
Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators.
Cancer Cell
; 41(5): 933-949.e11, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37116491
8.
Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer.
Cancer Cell
; 41(11): 1972-1988.e5, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37922910
9.
Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I-III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial.
Nat Commun
; 14(1): 8435, 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38114518
10.
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
Cancer Cell
; 41(7): 1207-1221.e12, 2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37327789
11.
Longitudinal Immune Profiling Reveals Unique Myeloid and T-cell Phenotypes Associated with Spontaneous Immunoediting in a Prostate Tumor Model.
Cancer Immunol Res
; 9(5): 529-541, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33637604
12.
High potency STING agonists engage unique myeloid pathways to reverse pancreatic cancer immune privilege.
J Immunother Cancer
; 9(8)2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34341132
13.
Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses.
Clin Cancer Res
; 27(2): 608-621, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33148676
14.
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.
Nat Genet
; 53(3): 332-341, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33649592
15.
Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype.
Cancer Immunol Res
; 8(11): 1365-1380, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32917656
16.
TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma.
J Immunother Cancer
; 7(1): 323, 2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31771649
17.
Author Correction: Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I-III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial.
Nat Commun
; 15(1): 225, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172131
18.
Activation of 4-1BB on Liver Myeloid Cells Triggers Hepatitis via an Interleukin-27-Dependent Pathway.
Clin Cancer Res
; 24(5): 1138-1151, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301830
19.
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy.
J Clin Invest
; 128(11): 5137-5149, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30188869
20.
Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity.
Cancer Immunol Res
; 5(8): 676-684, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28674082